JoF, Free Full-Text
Por um escritor misterioso
Descrição
Paracoccidioidomycosis (PCM) is a systemic mycosis caused by fungi of the genus Paracoccidioides and the different clinical forms of the disease are associated with the host immune responses. Quantitative trait loci mapping analysis was performed to assess genetic variants associated with mononuclear-cells-derived cytokines induced by P. brasiliensis on 158 individuals. We identified the rs11053595 SNP, which is present in the CLEC7A gene (encodes the Dectin-1 receptor) and the rs62290169 SNP located in the PROM1 gene (encodes CD133) associated with the production of IL-1β and IL-22, respectively. Functionally, the blockade of the dectin-1 receptor abolished the IL-1β production in P. brasiliensis-stimulated PBMCs. Moreover, the rs62290169-GG genotype was associated with higher frequency of CD38+ Th1 cells in PBMCs cultured with P. brasiliensis yeasts. Therefore, our research indicates that the CLEC7A and PROM1 genes are important for the cytokine response induced by P. brasiliensis and may influence the Paracoccidioidomycosis disease outcome.
Just Another Foundry – JAF Johannes
Jo's Styles Font Download
Letterhead Fonts / LHF Jalopy Joe / Period Fonts
S4 League Male Itc - Colaboratory
Jo Font : Download For Free, View Sample Text, Rating And More On
Open Access Journals - HTC Library
Term Papers Online: 90+ FREE Websites for Your Paper
Joe Jack Font - 1001 Free Fonts
The HighWire archive consists of 7,100,000 articles and 3,500,000 free full- text articles that could be stor…
Guided paragraph writing : a first course in English composition with structural practice : Jupp, T. C. (Thomas Cyprian) : Free Download, Borrow, and Streaming : Internet Archive
Journal of Fungi An Open Access Journal from MDPI
Tesla boosts referral program to help sales, $1,000 off, and 3 months of free Full Self-Driving
de
por adulto (o preço varia de acordo com o tamanho do grupo)